5α-Dihydroaldosterone
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IUPAC name 11β,21-Dihydroxy-3,20-dioxo-5α-pregnan-18-al | |
Preferred IUPAC name (1S,3aS,3bS,5aS,9aS,9bS,10S,11aR)-10-Hydroxy-1-(hydroxyacetyl)-9a-methyl-7-oxohexadecahydro-11aH-cyclopenta[a]phenanthrene-11a-carbaldehyde | |
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Properties | |
Chemical formula | C21H30O5 |
Molar mass | 362.466 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
5α-Dihydroaldosterone is a metabolite of aldosterone that is formed by 5α-reductase.[1] It is a potent antinatriuretic agent similarly to but somewhat different from aldosterone.[1] It is produced in the kidneys.[1]
References
- ^ a b c Azzouni F, Godoy A, Li Y, Mohler J (2012). "The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases". Adv Urol. 2012: 530121. doi:10.1155/2012/530121. PMC 3253436. PMID 22235201.
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Endogenous steroids
- Cholesterol
- 22R-Hydroxycholesterol
- 20α,22R-Dihydroxycholesterol
- Pregnenolone
- 11β-Hydroxypregnenolone
- 17α-Hydroxypregnenolone
- 21-Hydroxypregnenolone
- 17α,21-Dihydroxypregnenolone
- 11β,17α,21-Trihydroxypregnenolone
- Cholestanes: 24S-Hydroxycholesterol
- Cholesterol
- Pregnanes: 3α-Dihydroprogesterone
- 3β-Dihydroprogesterone
- 5α-Dihydrocorticosterone
- 5α-Dihydroprogesterone
- 5β-Dihydroprogesterone
- Allopregnanolone
- Corticosterone
- DHC
- DHDOC
- 11-Deoxycorticosterone
- Epipregnanolone
- Isopregnanolone
- Pregnanolone
- Pregnenolone
- Pregnenolone sulfate
- Progesterone
- THB
- THDOC
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