Cycrimine
Chemical compound
- US FDA: Cycrimine
- none
- 1-Cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
- 77-39-4
- 2911
- DB00942
- 2808
- 543567RFQQ
- CHEBI:59692 Y
- ChEMBL1201227
- DTXSID50861769
- Interactive image
- OC(CCN1CCCCC1)(C2CCCC2)c3ccccc3
InChI
- InChI=1S/C19H29NO/c21-19(18-11-5-6-12-18,17-9-3-1-4-10-17)13-16-20-14-7-2-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
- Key:SWRUZBWLEWHWRI-UHFFFAOYSA-N
Cycrimine (trade name Pagitane) is a central anticholinergic drug designed to reduce the levels of acetylcholine in the treatment of Parkinson's disease. Its mechanism of action is to bind to the muscarinic acetylcholine receptor M1.[1]
Synthesis
See also
References
- ^ Usdin E, Efron DH, eds. (1979). Psychotropic Drugs and Related Compounds (2nd ed.). Washington, DC: Pergamon Press. p. 218. ISBN 978-0-08-025510-1. OCLC 715151908.
- ^ Denton JJ, Schedl HP, Lawson VA, Neier WB (1950). "Antispasmodics. VII.1 Additional Morpholinyl and Piperidyl Tertiary Alcohols". Journal of the American Chemical Society. 72 (8): 3795–3796. doi:10.1021/ja01164a127.
External links
- Cycrimine at DrugLib.com