Protein-coding gene in the species Homo sapiens
FOXS1 |
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Identifiers |
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Aliases | FOXS1, FKHL18, FREAC10, forkhead box S1 |
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External IDs | OMIM: 602939; MGI: 95546; HomoloGene: 20871; GeneCards: FOXS1; OMA:FOXS1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 20 (human)[1] |
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| Band | 20q11.21 | Start | 31,844,303 bp[1] |
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End | 31,845,604 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 H1 | Start | 152,773,818 bp[2] |
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End | 152,775,128 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right coronary artery
- left coronary artery
- ascending aorta
- testicle
- Descending thoracic aorta
- popliteal artery
- tibial arteries
- apex of heart
- tibial nerve
- right auricle
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| Top expressed in | - external carotid artery
- internal carotid artery
- embryo
- sciatic nerve
- muscle of thigh
- Gonadal ridge
- right kidney
- stroma of bone marrow
- spermatocyte
- endothelial cell of lymphatic vessel
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - DNA-binding transcription factor activity
- DNA binding
- sequence-specific DNA binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- DNA-binding transcription factor activity, RNA polymerase II-specific
| Cellular component | | Biological process | - blood vessel development
- negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- negative regulation of DNA-binding transcription factor activity
- neuromuscular process controlling balance
- transcription, DNA-templated
- positive regulation of multicellular organism growth
- negative regulation of transcription by RNA polymerase II
- anatomical structure morphogenesis
- cell differentiation
- regulation of transcription by RNA polymerase II
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 20: 31.84 – 31.85 Mb | Chr 2: 152.77 – 152.78 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene. [5]
Function
The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000179772 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074676 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Forkhead box S1". Retrieved 2018-01-07.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.