KSR2 |
---|
|
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
|
|
Identifiers |
---|
Aliases | KSR2, kinase suppressor of ras 2 |
---|
External IDs | OMIM: 610737; MGI: 3610315; HomoloGene: 45469; GeneCards: KSR2; OMA:KSR2 - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 12 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Ideogram_human_chromosome_12.svg/300px-Ideogram_human_chromosome_12.svg.png) | Chr. | Chromosome 12 (human)[1] |
---|
| Band | 12q24.22-q24.23 | Start | 117,453,012 bp[1] |
---|
End | 117,968,990 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 5 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_5.svg/260px-Ideogram_house_mouse_chromosome_5.svg.png) | Chr. | Chromosome 5 (mouse)[2] |
---|
| Band | 5|5 F | Start | 117,552,065 bp[2] |
---|
End | 117,913,068 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - Brodmann area 23
- middle temporal gyrus
- postcentral gyrus
- endothelial cell
- entorhinal cortex
- superior frontal gyrus
- primary visual cortex
- buccal mucosa cell
- cerebellar vermis
- Brodmann area 46
|
| Top expressed in | - zygote
- dentate gyrus of hippocampal formation granule cell
- primary visual cortex
- superior frontal gyrus
- cerebellar cortex
- secondary oocyte
- lumbar subsegment of spinal cord
- neural layer of retina
- hippocampus proper
- amygdala
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - transferase activity
- nucleotide binding
- protein serine/threonine kinase activity
- ATP binding
- metal ion binding
- kinase activity
- protein kinase activity
- signal transducer activity
- protein binding
| Cellular component | - cytoplasm
- membrane
- cytosol
- plasma membrane
| Biological process | - intracellular signal transduction
- phosphorylation
- protein phosphorylation
- Ras protein signal transduction
- calcium-mediated signaling
- positive regulation of MAPK cascade
- positive regulation of cold-induced thermogenesis
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
NM_001034873 NM_001114545 NM_001312914 |
|
---|
RefSeq (protein) | | |
---|
Location (UCSC) | Chr 12: 117.45 – 117.97 Mb | Chr 5: 117.55 – 117.91 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|