OR6C75

Protein-coding gene in the species Homo sapiens
OR6C75
Identifiers
AliasesOR6C75, olfactory receptor family 6 subfamily C member 75
External IDsMGI: 3030624; HomoloGene: 74101; GeneCards: OR6C75; OMA:OR6C75 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for OR6C75
Genomic location for OR6C75
Band12q13.2Start55,362,975 bp[1]
End55,369,279 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for OR6C75
Genomic location for OR6C75
Band10|10 D3Start129,334,361 bp[2]
End129,339,211 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad

  • sural nerve

  • ventricular zone
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

390323

258935

Ensembl

ENSG00000187857

ENSMUSG00000044025

UniProt

A6NL08

Q8VGJ3

RefSeq (mRNA)

NM_001005497

NM_146933

RefSeq (protein)

NP_001005497

NP_667144

Location (UCSC)Chr 12: 55.36 – 55.37 MbChr 10: 129.33 – 129.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor, family 6, subfamily C, member 75 is a protein in humans that is encoded by the OR6C75 gene. [5]

Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter receptors and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187857 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044025 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Olfactory receptor, family 6, subfamily C, member 75". Retrieved 2012-11-26.
  6. ^ [provided by RefSeq, Jul 2008]

Further reading


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