FOXC2 |
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Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants |
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Aliases | FOXC2 |
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IDs externes | OMIM: 602402 MGI: 1347481 HomoloGene: 21091 GeneCards: FOXC2 |
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Position du gène (Homme) |
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| Chr. | Chromosome 16 humain[1] |
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| Locus | 16q24.1 | Début | 86,566,829 bp[1] |
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Fin | 86,569,728 bp[1] |
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Position du gène (Souris) |
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| Chr. | Chromosome 8 (souris)[2] |
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| Locus | 8 E1|8 70.33 cM | Début | 121,842,910 bp[2] |
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Fin | 121,845,634 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - veine cave
- palpebral conjunctiva
- artère poplitée
- Ganglion de Gasser
- Tibial arteries
- urètre
- aorte ascendante
- ganglion sensitif d’un nerf spinal
- Descending thoracic aorta
- cardiac muscle tissue of right atrium
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| Fortement exprimé dans | - arc aortique
- aorte ascendante
- cinquième métatarsien
- corpuscule rénal
- nerf optique
- valve aortique
- quatrième métatarsien
- somite
- Sclérotome
- lumbar spinal ganglion
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| Plus de données d'expression de référence |
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BioGPS | |
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Gene Ontology |
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Fonction moléculaire | - sequence-specific DNA binding
- liaison ADN
- DNA-binding transcription factor activity
- DNA-binding transcription activator activity, RNA polymerase II-specific
- liaison protéique
- identical protein binding
- transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
- chromatin DNA binding
- promoter-specific chromatin binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
| Composant cellulaire | - noyau
- nucléoplasme
- corps nucléaire
| Processus biologique | - voie de signalisation Notch
- Somitogenèse
- embryonic skeletal system morphogenesis
- skeletal system development
- insulin receptor signaling pathway
- ureteric bud development
- regulation of transcription, DNA-templated
- positive regulation of cell migration involved in sprouting angiogenesis
- neural crest cell development
- paraxial mesoderm formation
- paraxial mesodermal cell fate commitment
- ostéogenèse
- lymphangiogenesis
- collagen fibril organization
- kidney development
- glomerular mesangial cell development
- heart morphogenesis
- negative regulation of transcription by RNA polymerase II
- cardiac muscle cell proliferation
- lymph vessel development
- transcription, DNA-templated
- embryonic heart tube development
- positive regulation of endothelial cell migration
- régulation positive de la transcription dépendante de l'ADN
- développent d'un organisme multicellulaire
- ventricular cardiac muscle tissue morphogenesis
- développement du cœur
- blood vessel remodeling
- vascular endothelial growth factor receptor signaling pathway
- blood vessel development
- positive regulation of vascular wound healing
- artery morphogenesis
- branching involved in blood vessel morphogenesis
- glomerular visceral epithelial cell differentiation
- response to hormone
- embryonic viscerocranium morphogenesis
- embryonic cranial skeleton morphogenesis
- camera-type eye development
- glomerular endothelium development
- positive regulation of cell adhesion mediated by integrin
- mesoderm development
- regulation of organ growth
- metanephros development
- prolifération cellulaire
- positive regulation of transcription by RNA polymerase II
- negative regulation of apoptotic process involved in outflow tract morphogenesis
- transcription by RNA polymerase II
- différenciation cellulaire
- regulation of transcription by RNA polymerase II
- morphogenèse d'une structure anatomique
- negative regulation of cold-induced thermogenesis
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protéine) | | |
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Localisation (UCSC) | Chr 16: 86.57 – 86.57 Mb | Chr 8: 121.84 – 121.85 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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