Daf-5

Protein-coding gene in the species Caenorhabditis elegans
Dauer Formation abnormality gene 5
Identifiers
OrganismCaenorhabditis elegans
SymbolDaf-5
Entrez175054
RefSeq (mRNA)NM_064540.5
RefSeq (Prot)NP_496941.1
UniProtG5EDM7
Other data
ChromosomeII: 14.03 - 14.04 Mb
Search for
StructuresSwiss-model
DomainsInterPro

Daf-5 is an ortholog of the mammalian protein Sno/Ski，which present in the nematode worm Caenorhabditis elegans on the downstream of TGFβ signaling pathway.[1] Without daf-7 signal, daf-5 combined with daf-3, co-SMAD for C. elegans, to form a heterodimer and started dauer development.[2]

References

  1. ^ da Graca LS, Zimmerman KK, Mitchell MC, Kozhan-Gorodetska M, Sekiewicz K, Morales Y, Patterson GI (January 2004). "DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGF beta pathway to regulate C. elegans dauer development". Development. 131 (2): 435–46. doi:10.1242/dev.00922. PMID 14681186. S2CID 31708102.
  2. ^ Gumienny TL, Savage-Dunn C (July 2013). "TGF-β signaling in C. elegans". WormBook: 1–34. doi:10.1895/wormbook.1.22.2. PMC 5081272. PMID 23908056.
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Dauer Formation Abnormal protein
  • Daf-1
  • Daf-2
  • Daf-3
  • Daf-4
  • Daf-5
  • Daf-6
  • Daf-7
  • Daf-8
  • Daf-9
  • Daf-10
  • Daf-11
  • Daf-12
  • Daf-14
  • Daf-15
  • Daf-16
  • Daf-18
  • Daf-19
  • Daf-21
  • Daf-22
  • Daf-23
  • Daf-25
  • Daf-28
  • Daf-31
  • Daf-36
  • Daf-37
  • Daf-38
  • Daf-41
  • Daf-42
Downstream Of Daf protein
  • Dod-3
  • Dod-6
  • Dod-13
  • Dod-17
  • Dod-18
  • Dod-19
  • Dod-20
  • Dod-21
  • Dod-22
  • Dod-23
  • Dod-24
Daf-12-interacting protein
  • Din-1
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