Lexatumumab
Monoclonal antibody
NY (what is this?) (verify) Lexatumumab (also known as ETR2-ST01) is an experimental agonistic human monoclonal antibody against TRAIL-R2 (DR5, APO-2), intended for the treatment of cancer.[1][2]
HGS-ETR2 antibodies were generated by Human Genome Sciences through a collaboration with Cambridge Antibody Technology.[3]
Development was discontinued in 2015.[4]
References
- ^ "Statement on a Nonproprietary Name adopted by the USAN Council - Lexatumumab" (PDF). American Medical Association. Archived from the original (PDF) on 2012-02-20.
- ^ Marini P (December 2006). "Drug evaluation: lexatumumab, an intravenous human agonistic mAb targeting TRAIL receptor 2". Current Opinion in Molecular Therapeutics. 8 (6): 539–46. PMID 17243490.
- ^ "TRAIL Receptor Antibodies". Human Genome Sciences, Inc. Archived from the original on 2008-05-16. Retrieved 2010-05-12.
- ^ "Lexatumumab". AdisInsight. Springer Nature Switzerland AG.
- v
- t
- e
Monoclonal antibodies for tumors
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e