Nacolomab tafenatox
Schematic image of nacolomab tafenatox: VH, VL: variable (antigen binding) domains of antibody fragment CH1, CL: constant domains of antibody fragment | |
Monoclonal antibody | |
---|---|
Type | Fab fragment |
Source | Mouse |
Target | colorectal tumor antigen C242 |
Clinical data | |
ATC code | NY (what is this?) (verify) |
Nacolomab tafenatox is a mouse monoclonal antibody.[1][2] The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).[1]
See also
- Naptumomab estafenatox, a drug with a similar chemical structure and mechanism
References
- ^ a b "Recommended INN List: Nacolomab tafenatox" (PDF). WHO Drug Information. 9 (3): 182. 1995. Archived from the original (PDF) on 23 February 2012.
- ^ Alpaugh RK, Weiner LM, Persson B, Persson R, Dohlsten M, Kalland T (1997). "Nacolomab Tafenatox". Drugs of the Future. 22 (11): 1226–30.
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Monoclonal antibodies for tumors
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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