OR4K17

Protein-coding gene in the species Homo sapiens
OR4K17
Identifiers
AliasesOR4K17, OR14-29, olfactory receptor family 4 subfamily K member 17
External IDsHomoloGene: 105276; GeneCards: OR4K17; OMA:OR4K17 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for OR4K17
Genomic location for OR4K17
Band14q11.2Start20,110,739 bp[1]
End20,122,199 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • liver
    n/a
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

390436

n/a

Ensembl

ENSG00000176230

n/a

UniProt

Q8NGC6

n/a

RefSeq (mRNA)

NM_001004715

n/a

RefSeq (protein)

NP_001004715

n/a

Location (UCSC)Chr 14: 20.11 – 20.12 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 4K17 is a protein that in humans is encoded by the OR4K17 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176230 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR4K17 olfactory receptor, family 4, subfamily K, member 17".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
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Class II
(tetrapod specific receptors)
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