DLX2 |
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Identifiers |
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Aliases | DLX2, TES-1, TES1, AW121999, Dlx-2, distal-less homeobox 2 |
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External IDs | OMIM: 126255; MGI: 94902; HomoloGene: 3244; GeneCards: DLX2; OMA:DLX2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q31.1 | Start | 172,099,438 bp[1] |
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End | 172,102,900 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2 C2|2 42.65 cM | Start | 71,373,752 bp[2] |
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End | 71,377,098 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gonad
- buccal mucosa cell
- sperm
- ganglionic eminence
- periodontal fiber
- pericardium
- ventricular zone
- Brodmann area 23
- middle temporal gyrus
- superior frontal gyrus
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| Top expressed in | - Rostral migratory stream
- medial ganglionic eminence
- tooth
- molar
- tooth germ
- Enamel organ
- olfactory bulb
- hair follicle
- lateral septal nucleus
- enteric nervous system
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- sequence-specific DNA binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- DNA-binding transcription factor activity
- DNA-binding transcription activator activity, RNA polymerase II-specific
- chromatin binding
- protein binding
- single-stranded RNA binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
| Cellular component | | Biological process | - cerebral cortex GABAergic interneuron differentiation
- proximal/distal pattern formation
- cell differentiation
- regulation of transcription, DNA-templated
- regulation of transcription by RNA polymerase II
- negative regulation of transcription by RNA polymerase II
- transcription by RNA polymerase II
- branching morphogenesis of a nerve
- embryonic skeletal system development
- multicellular organism development
- odontogenesis of dentin-containing tooth
- cerebral cortex GABAergic interneuron fate commitment
- cartilage development
- brain development
- negative regulation of oligodendrocyte differentiation
- forebrain neuron differentiation
- embryonic cranial skeleton morphogenesis
- olfactory bulb development
- hippocampus development
- subpallium development
- negative regulation of Notch signaling pathway
- positive regulation of transcription by RNA polymerase II
- positive regulation of cell differentiation
- negative regulation of photoreceptor cell differentiation
- positive regulation of amacrine cell differentiation
- transcription, DNA-templated
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 2: 172.1 – 172.1 Mb | Chr 2: 71.37 – 71.38 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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