TLX2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | TLX2, HOX11L1, NCX, T-cell leukemia homeobox 2, T cell leukemia homeobox 2 |
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External IDs | OMIM: 604240; MGI: 1350935; HomoloGene: 7575; GeneCards: TLX2; OMA:TLX2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2p13.1 | Start | 74,513,463 bp[1] |
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End | 74,517,148 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6 C3|6 35.94 cM | Start | 83,045,305 bp[2] |
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End | 83,047,274 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gonad
- transverse colon
- mucosa of transverse colon
- muscle layer of sigmoid colon
- right testis
- left testis
- primary visual cortex
- rectum
- duodenum
- appendix
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| Top expressed in | - lumbar spinal ganglion
- adrenal medulla
- autonomic nervous system
- glossopharyngeal ganglion
- parasympathetic nervous system
- female urethra
- male urethra
- autonomic ganglion
- sympathetic nervous system
- cervical ganglion
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- sequence-specific DNA binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- DNA-binding transcription factor activity
| Cellular component | - cytoplasm
- nucleus
- cellular component
| Biological process | - multicellular organism development
- enteric nervous system development
- mesoderm formation
- regulation of transcription, DNA-templated
- negative regulation of dendrite morphogenesis
- transcription, DNA-templated
- transcription by RNA polymerase II
- positive regulation of transcription by RNA polymerase II
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 2: 74.51 – 74.52 Mb | Chr 6: 83.05 – 83.05 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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