HES6 |
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Identifiers |
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Aliases | HES6, C-HAIRY1, HES-6, bHLHb41, bHLHc23, hes family bHLH transcription factor 6 |
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External IDs | OMIM: 610331; MGI: 1859852; HomoloGene: 23111; GeneCards: HES6; OMA:HES6 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q37.3 | Start | 238,238,267 bp[1] |
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End | 238,240,662 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 D | Start | 91,339,205 bp[2] |
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End | 91,341,760 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ganglionic eminence
- ventricular zone
- secondary oocyte
- C1 segment
- mucosa of transverse colon
- anterior pituitary
- Brodmann area 9
- primary visual cortex
- cingulate gyrus
- anterior cingulate cortex
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| Top expressed in | - ventricular zone
- fossa
- right kidney
- internal carotid artery
- adrenal gland
- saccule
- ganglionic eminence
- left lobe of liver
- Paneth cell
- proximal tubule
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- transcription factor binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- protein dimerization activity
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- DNA-binding transcription factor activity
- transcription coregulator activity
- DNA-binding transcription factor activity, RNA polymerase II-specific
- transcription corepressor activity
- sequence-specific DNA binding
- sequence-specific double-stranded DNA binding
| Cellular component | - nucleus
- transcription regulator complex
| Biological process | - regulation of transcription by RNA polymerase II
- multicellular organism development
- cell differentiation
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
- nervous system development
- regulation of transcription, DNA-templated
- somitogenesis
- Notch signaling pathway
- regulation of neurogenesis
- anterior/posterior pattern specification
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_018645 NM_001142853 NM_001282434 |
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NM_019479 NM_001360899 NM_001360900 |
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RefSeq (protein) | |
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NP_001136325 NP_001269363 NP_061115 |
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NP_062352 NP_001347828 NP_001347829 |
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Location (UCSC) | Chr 2: 238.24 – 238.24 Mb | Chr 1: 91.34 – 91.34 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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