HEYL |
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Identifiers |
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Aliases | HEYL, HESR3, HEY3, HRT3, bHLHb33, hes related family bHLH transcription factor with YRPW motif-like, hes related family bHLH transcription factor with YRPW motif like |
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External IDs | OMIM: 609034; MGI: 1860511; HomoloGene: 8494; GeneCards: HEYL; OMA:HEYL - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1p34.2 | Start | 39,623,435 bp[1] |
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End | 39,639,643 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4|4 D2.2 | Start | 123,127,349 bp[2] |
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End | 123,143,668 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right coronary artery
- left coronary artery
- body of pancreas
- tibial arteries
- ascending aorta
- apex of heart
- right auricle
- Descending thoracic aorta
- right lung
- left ventricle
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| Top expressed in | - ascending aorta
- vasculature of trunk
- external carotid artery
- aortic valve
- internal carotid artery
- pelvic ganglion
- spinal nerve
- urethra
- female urethra
- tunica media of zone of aorta
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - microsatellite binding
- DNA binding
- sequence-specific DNA binding
- transcription corepressor activity
- protein dimerization activity
- protein homodimerization activity
- DNA-binding transcription factor activity
- DNA-binding transcription activator activity, RNA polymerase II-specific
- transcription factor binding
- protein binding
- protein heterodimerization activity
- AF-1 domain binding
- RNA polymerase II core promoter sequence-specific DNA binding
- RNA polymerase II general transcription initiation factor activity
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- sequence-specific double-stranded DNA binding
| Cellular component | - nucleoplasm
- nucleus
- cytoplasm
| Biological process | - regulation of transcription, DNA-templated
- negative regulation of androgen receptor signaling pathway
- cellular response to BMP stimulus
- glomerulus development
- transcription by RNA polymerase II
- negative regulation of gene expression
- transcription, DNA-templated
- multicellular organism development
- proximal tubule development
- skeletal muscle cell differentiation
- Notch signaling pathway
- negative regulation of transcription by RNA polymerase II
- positive regulation of neuron differentiation
- positive regulation of transcription by RNA polymerase II
- outflow tract morphogenesis
- atrioventricular valve morphogenesis
- cardiac ventricle morphogenesis
- cardiac epithelial to mesenchymal transition
- mesenchymal cell development
- pulmonary valve morphogenesis
- epithelial to mesenchymal transition involved in endocardial cushion formation
- ventricular septum morphogenesis
- endocardial cushion morphogenesis
- negative regulation of transcription, DNA-templated
- positive regulation of transcription of Notch receptor target
- blood vessel development
- heart development
- cell differentiation
- regulation of neurogenesis
- negative regulation of DNA-binding transcription factor activity
- aortic valve morphogenesis
- Notch signaling involved in heart development
- anterior/posterior pattern specification
- circulatory system development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 39.62 – 39.64 Mb | Chr 4: 123.13 – 123.14 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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