SOX8 |
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Identifiers |
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Aliases | SOX8, SRY-box 8, SRY-box transcription factor 8 |
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External IDs | OMIM: 605923; MGI: 98370; HomoloGene: 7950; GeneCards: SOX8; OMA:SOX8 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 16 (human)[1] |
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| Band | 16p13.3 | Start | 981,770 bp[1] |
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End | 986,979 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17 A3.3|17 12.69 cM | Start | 25,784,866 bp[2] |
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End | 25,789,660 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - inferior ganglion of vagus nerve
- external globus pallidus
- subthalamic nucleus
- parotid gland
- pars reticulata
- ventral tegmental area
- medulla oblongata
- spinal cord
- C1 segment
- superior vestibular nucleus
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| Top expressed in | - metatarsal bones
- lumbar subsegment of spinal cord
- zygote
- fourth metatarsal bone
- Bowman's capsule
- second metatarsal bone
- visual cortex
- third metatarsal bone
- primary visual cortex
- secondary oocyte
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - DNA binding
- sequence-specific DNA binding
- DNA-binding transcription factor activity
- transcription factor binding
- protein heterodimerization activity
- RNA polymerase II core promoter sequence-specific DNA binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- DNA-binding transcription activator activity, RNA polymerase II-specific
| Cellular component | | Biological process | - positive regulation of osteoblast proliferation
- cell fate commitment
- negative regulation of myoblast differentiation
- positive regulation of branching involved in ureteric bud morphogenesis
- male gonad development
- peripheral nervous system development
- regulation of transcription, DNA-templated
- morphogenesis of a branching epithelium
- ureter morphogenesis
- regulation of hormone levels
- oligodendrocyte differentiation
- negative regulation of apoptotic process
- in utero embryonic development
- cell maturation
- Sertoli cell development
- transcription, DNA-templated
- metanephric nephron tubule formation
- positive regulation of transcription, DNA-templated
- negative regulation of photoreceptor cell differentiation
- enteric nervous system development
- renal vesicle induction
- positive regulation of kidney development
- positive regulation of gene expression
- retina development in camera-type eye
- astrocyte fate commitment
- osteoblast differentiation
- neural crest cell migration
- spermatogenesis
- retinal rod cell differentiation
- skeletal muscle cell differentiation
- adipose tissue development
- negative regulation of transcription, DNA-templated
- fat cell differentiation
- signal transduction
- positive regulation of transcription by RNA polymerase II
- positive regulation of gliogenesis
- morphogenesis of an epithelium
- central nervous system development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 16: 0.98 – 0.99 Mb | Chr 17: 25.78 – 25.79 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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