NKX2-3 |
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Identifiers |
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Aliases | NKX2-3, CSX3, NK2.3, NKX2.3, NKX2C, NKX4-3, NK2 homeobox 3 |
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External IDs | OMIM: 606727; MGI: 97348; HomoloGene: 17061; GeneCards: NKX2-3; OMA:NKX2-3 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 10 (human)[1] |
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| Band | 10q24.2 | Start | 99,532,942 bp[1] |
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End | 99,536,524 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 19 (mouse)[2] |
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| Band | 19 C3|19 36.67 cM | Start | 43,600,764 bp[2] |
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End | 43,604,331 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - muscle layer of sigmoid colon
- spleen
- transverse colon
- duodenum
- sural nerve
- minor salivary glands
- jejunal mucosa
- mucosa of transverse colon
- cecum
- rectum
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| Top expressed in | - Hindgut
- migratory enteric neural crest cell
- yolk sac
- Stomodeum
- buccopharyngeal membrane
- duodenum
- pharyngeal pouch
- ileum
- tongue
- embryo
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - sequence-specific DNA binding
- DNA binding
- molecular function
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription factor activity
| Cellular component | - nucleus
- cellular component
| Biological process | - leukocyte homeostasis
- CD4-positive, alpha-beta T cell differentiation
- post-embryonic digestive tract morphogenesis
- regulation of transcription, DNA-templated
- plasma cell differentiation
- spleen development
- post-embryonic development
- transcription, DNA-templated
- macrophage differentiation
- mucosa-associated lymphoid tissue development
- odontogenesis of dentin-containing tooth
- gland morphogenesis
- regulation of cell population proliferation
- immune response
- B cell differentiation
- Peyer's patch development
- digestive tract development
- lymph node development
- triglyceride metabolic process
- leukocyte migration
- positive regulation of transcription by RNA polymerase II
- biological process
- cell differentiation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 10: 99.53 – 99.54 Mb | Chr 19: 43.6 – 43.6 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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