HMGB4 |
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Identifiers |
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Aliases | HMGB4, dJ1007G16.5, high mobility group box 4 |
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External IDs | OMIM: 617285; MGI: 1916567; HomoloGene: 83321; GeneCards: HMGB4; OMA:HMGB4 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1p35.1 | Start | 33,860,475 bp[1] |
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End | 33,864,791 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4|4 D2.2 | Start | 128,154,005 bp[2] |
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End | 128,154,750 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right testis
- left testis
- sperm
- testicle
- tail of epididymis
- right coronary artery
- caput epididymis
- ectocervix
- right uterine tube
- canal of the cervix
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| Top expressed in | - seminiferous tubule
- spermatid
- spermatocyte
- muscle tissue
- central gray substance of midbrain
- striated muscle tissue
- pancreas
- skeletal muscle tissue
- islet of Langerhans
- hypothalamus
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein binding
- DNA binding
- transcription factor binding
- DNA binding, bending
| Cellular component | - nucleus
- chromosome
- cytoplasm
| Biological process | - activation of innate immune response
- DNA recombination
- chromatin remodeling
- regulation of transcription by RNA polymerase II
- regulation of signaling receptor activity
- positive regulation of autophagy
- developmental process
- positive regulation of interleukin-6 production
- positive regulation of tumor necrosis factor production
- positive regulation of innate immune response
- positive regulation of transcription by RNA polymerase II
- cell chemotaxis
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of NIK/NF-kappaB signaling
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_145205 NM_001352984 NM_001379301 |
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RefSeq (protein) | |
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NP_660206 NP_001339913 NP_001366230 |
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Location (UCSC) | Chr 1: 33.86 – 33.86 Mb | Chr 4: 128.15 – 128.15 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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