ZBTB7B |
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Identifiers |
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Aliases | ZBTB7B, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX, CKROX, zinc finger and BTB domain containing 7B |
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External IDs | OMIM: 607646; MGI: 102755; HomoloGene: 7605; GeneCards: ZBTB7B; OMA:ZBTB7B - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1q21.3 | Start | 155,002,630 bp[1] |
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End | 155,018,523 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3 F1|3 39.09 cM | Start | 89,284,951 bp[2] |
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End | 89,302,083 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - monocyte
- mucosa of transverse colon
- skin of abdomen
- skin of leg
- granulocyte
- nipple
- cardia
- body of stomach
- salivary gland
- mucosa of pharynx
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| Top expressed in | - granulocyte
- pyloric antrum
- lip
- neural layer of retina
- tibiofemoral joint
- esophagus
- lens
- yolk sac
- muscle of thigh
- gastric mucosa
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- protein binding
- metal ion binding
- nucleic acid binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- DNA-binding transcription factor activity
- DNA-binding transcription factor activity, RNA polymerase II-specific
- cis-regulatory region sequence-specific DNA binding
- protein homodimerization activity
- histone deacetylase binding
| Cellular component | | Biological process | - multicellular organism development
- ectoderm development
- cell differentiation
- regulation of transcription, DNA-templated
- transcription by RNA polymerase II
- transcription, DNA-templated
- regulation of CD4-positive, alpha-beta T cell differentiation
- regulation of CD8-positive, alpha-beta T cell differentiation
- positive regulation of transcription by RNA polymerase II
- regulation of gene expression
- negative regulation of T-helper 17 cell differentiation
- lactation
- positive regulation of gene expression
- response to insulin
- positive regulation of CD4-positive, alpha-beta T cell differentiation
- negative regulation of CD8-positive, alpha-beta T cell differentiation
- positive regulation of insulin receptor signaling pathway
- positive regulation of brown fat cell differentiation
- adaptive thermogenesis
- positive regulation of SREBP signaling pathway
- negative regulation of transcription by RNA polymerase II
- NK T cell differentiation
- negative regulation of gene expression
- positive regulation of histone deacetylation
- negative regulation of NK T cell proliferation
- positive regulation of cold-induced thermogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001252406 NM_001256455 NM_001377451 NM_001377452 NM_001377453
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NM_001377454 NM_001377455 |
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NM_009565 NM_001355206 NM_001355211 NM_001355212 |
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RefSeq (protein) | NP_001239335 NP_001243384 NP_001364380 NP_001364381 NP_001364382
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NP_001364383 NP_001364384 |
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NP_033591 NP_001342135 NP_001342140 NP_001342141 |
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Location (UCSC) | Chr 1: 155 – 155.02 Mb | Chr 3: 89.28 – 89.3 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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