HES3 |
---|
|
Identifiers |
---|
Aliases | HES3, bHLHb43, hes family bHLH transcription factor 3 |
---|
External IDs | OMIM: 609971; MGI: 104877; HomoloGene: 7358; GeneCards: HES3; OMA:HES3 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 1 (human)[1] |
---|
| Band | 1p36.31 | Start | 6,244,179 bp[1] |
---|
End | 6,245,578 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 4 (mouse)[2] |
---|
| Band | 4 E2|4 83.01 cM | Start | 152,370,429 bp[2] |
---|
End | 152,376,119 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - olfactory zone of nasal mucosa
|
| Top expressed in | - urethra
- male urethra
- female urethra
- cerebellar cortex
- embryo
- hair
- tail of embryo
- Purkinje cell
- adrenal medulla
- pars intermedia
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - DNA binding
- transcription factor binding
- protein dimerization activity
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- transcription corepressor activity
- sequence-specific DNA binding
- sequence-specific double-stranded DNA binding
| Cellular component | | Biological process | - hindbrain morphogenesis
- trochlear nerve development
- midbrain-hindbrain boundary morphogenesis
- negative regulation of transcription, DNA-templated
- in utero embryonic development
- negative regulation of transcription by RNA polymerase II
- regulation of transcription, DNA-templated
- regulation of timing of neuron differentiation
- regulation of neurogenesis
- oculomotor nerve development
- transcription, DNA-templated
- midbrain development
- positive regulation of transcription by RNA polymerase II
- neural tube development
- somitogenesis
- Notch signaling pathway
- cell differentiation
- anterior/posterior pattern specification
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protein) | | |
---|
NP_032263 NP_001390720 NP_001390721 NP_001390722 NP_001390723 |
|
---|
Location (UCSC) | Chr 1: 6.24 – 6.25 Mb | Chr 4: 152.37 – 152.38 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|