FOXK2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1JXS, 2C6Y |
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Identifiers |
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Aliases | FOXK2, ILF, ILF-1, ILF1, forkhead box K2, nGTBP |
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External IDs | OMIM: 147685; MGI: 1916087; HomoloGene: 18748; GeneCards: FOXK2; OMA:FOXK2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17q25.3 | Start | 82,519,713 bp[1] |
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End | 82,644,662 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 E2 | Start | 121,259,990 bp[2] |
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End | 121,309,896 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gastrocnemius muscle
- sural nerve
- ganglionic eminence
- oocyte
- muscle of thigh
- ventricular zone
- left testis
- right testis
- gingival epithelium
- sperm
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| Top expressed in | - zygote
- secondary oocyte
- cumulus cell
- ventricular zone
- ascending aorta
- renal corpuscle
- tail of embryo
- otic vesicle
- mandibular prominence
- spermatocyte
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - DNA-binding transcription factor activity
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- sequence-specific DNA binding
- DNA binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- protein binding
- magnesium ion binding
- metal ion binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- transcription cis-regulatory region binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
| Cellular component | - nucleus
- nucleoplasm
- cytoplasm
| Biological process | - regulation of transcription by RNA polymerase II
- regulation of transcription, DNA-templated
- positive regulation of transcription by RNA polymerase II
- transcription, DNA-templated
- transcription by RNA polymerase II
- protein deubiquitination
- anatomical structure morphogenesis
- cell differentiation
- negative regulation of transcription by RNA polymerase II
- cellular glucose homeostasis
- negative regulation of autophagy
- regulation of glucose metabolic process
- response to starvation
- negative regulation of transcription, DNA-templated
- positive regulation of transcription, DNA-templated
- canonical glycolysis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_004514 NM_181430 NM_181431 |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 17: 82.52 – 82.64 Mb | Chr 11: 121.26 – 121.31 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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